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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

威尔·史密斯早年成名,那是上世纪80年代末90年代初,他做嘻哈组合"DJ爵士杰夫&活力王子"的后期成员时。然而,虽然他赚得盆满钵盈,却不善于管理金钱。这真是个老掉牙的故事。名望、金钱扑面而来;却没有远见,空有一堆玩物,最终导致超支。对财产的监管意识与责任感的缺失,让他从富有的顶峰一下跌到破产的边缘。没落之后,他欠政府的退缴税一直没能偿还。
intentionally

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

这份榜单的四所英国大学分别是剑桥大学、牛津大学和伦敦大学和帝国理工学院。东京大学也位列前20名。
Xi Jinping and other leadershave made it clear that China is willing to accept a slower growth pace if thiswill allow for a more sustainable, consumer-driven expansion of its economy.Some prognosticators are quick to conclude that China’s economy will soonsignificantly slow down, especially because China’s economy has sputteredfollowing prior instances when the nation’s leaders have effected suchfundamental economic reforms (such as in 1978 and 1993).

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

The 2011 Nobel Peace Prize has been awarded to Liberian President Ellen Johnson Sirleaf, Liberian peace activist Leymah Gbowee and Yemeni women's rights advocate Tawakkul Karman.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

沙特王储穆罕默德·本·萨勒曼表示,多数被捕人员已同意归还部分非法获得的钱财,以换取自由。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 家居体验馆引领家装新潮流
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

在7月31日的分析师电话会议上,特斯拉的董事长兼CEO埃隆o穆斯克亲手给“特斯拉热”又添了一把柴。这次会议上爆出的“大新闻”并不是特斯拉第二季度产量再次提升并超过了收益预期。
“今年榜单有趣的地方之一是,尽管网站都开始实行更严的密码设定政策,位数少的密码仍出现在今年的榜单上。”
Armistice Day became an official U.S. holiday in 1938, and remained so until 1954, when it was renamed Veterans Day in the aftermath of both World War Two and the Korean War. It is separate from Memorial Day, which is observed on the last Monday in May and honors servicemen and women killed in war.
指尖陀螺

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

游戏平台:PlayStation 4
他也承认由于他和Vonnie已经离婚了所以听说这封信的时候感情有些复杂。
Beloved TV show characters enter our lives as friends and impact us in crazy ways. They can make us laugh until our sides hurt, cry when things don't go well for them, and call in sick to work when we just can't stop watching and must know what happens. But through it all, we love them. And yet, there's so much that the audience will never know. Some TV shows have dark secrets. Some almost didn't exist at all. Here are some behind the scenes stories of your favorite TV shows.
今年中国内地共有54所高校进入亚洲大学排行榜前300名。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

报告同时也显示,双十一已经成为由淘宝,天猫,京东领衔的电商的最大购物活动。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

以美元值计,11月中国的进口总值同比上升17.7%,比10月的17.2%高,高于11.3%的预期增速。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Scientists confirmed Monday that a skeleton found under a carpark in the English city of Leicester was that of King Richard III, in a bizarre end to a 500-year-old historical mystery.
Many entrepreneurs already have a Gmail address, but not every ‘trep knows about the power of Google Docs. By utilizing Google Docs, you can instantly create shareable documents, spreadsheets and presentations that can be updated by any team member with an Internet connection. Take that “track changes”!

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

The central government is planning to establish a bond market connect between the mainland and Hong Kong Special Administrative Region on a trial basis this year, allowing for the first time overseas capital to access mainland bond markets from overseas. Hong Kong will be the first to benefit from such an arrangement
他认为,地方政府通过卖地、强拆来追求GDP代价太大,早晚要还。“我愿意用一个政协委员的身份非常严肃地提出问题,我们是不是可以不要那么重视GDP?我们是不是可以选择减缓经济发展的速度?”

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

“这不是可持续的增长,因为它们并未被租出去,当地市场的喊价者们并不会购买。”
limited

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

最佳新人:Florida Georgia Line
Farewell to Don and his perfect suits, to Peggy and her plaids, to Joan and her jewel tones and sheaths.
The scientists’ analysis comes only a month after nearly 200 governments struck a new climate agreement in Paris that aims to stop global temperatures from rising more than 2C from pre-industrial levels, and ideally limit warming to 1.5C.
5. 艾玛?斯通

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

n. (准备好演出的)节目,保留剧目,(计算机的)指令表

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

The private Facebook group chat that led to offers of admission being rescinded was named, at one point, "Harvard memes for horny bourgeois teens", the Crimson reported.
罗塞略致力于改善公私合作伙伴关系,并使用这笔收入来挽救面临400亿美元的退休制度,预计不到一年就会崩溃。罗塞略也承诺与美国国会去年成立监督波多黎各财政的联邦控制委员会密切合作,他还说支持与债权人就协助重组一笔近700亿美元的公债谈判。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

201202/172834.shtmlChinese entrepreneur Wang Xing stays in touch with a sister in California and an uncle in Australia through chat software that offers a glimpse of how China's Internet companies can compete globally.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Foreigners with permanent residence enjoy the same rights as Chinese citizens, such as in investment, housing purchases and schooling, among other rights.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

The reason is twofold: For one, logistically, there are simply too many opportunities to get caught job searching. Résumé copies will be found. Computer servers will be checked. Co-workers will notice when you're clearly elsewhere, either literally for interviews or emotionally (more on that later)。
In a statement given to the website Kotaku, Epic Games said the lawsuit was a result of Mr Rogers "filing a DMCA counterclaim to a takedown notice on a YouTube video that exposed and promoted Fortnite Battle Royale cheats and exploits."
This year, several professions geared toward serving the financial and health needs of an aging population made the top ten, says Lee, including audiologist, financial planner, and physical therapist.
8.My resume is 5 pages long for a good reason. – Because I’m darn good at bullshittin’!

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
From the themed collection: 北京家具制造业拉开转移大幕
Review Article

Influenza neuraminidase: A druggable target for natural products

The American Film Institute has picked its 10 best movies and TV shows of the year. The titles, presented in alphabetical order, are works AFI's juries have determined advance the art of the moving image, enhance the cultural heritage of America's art form, inspire audiences and artists and make a mark on American society.
羽毛球、篮球、击剑、柔道、乒乓球、跆拳道、网球、举重、摔跤、室内排球、拳击、曲棍球#(&xYyCk,DE@+,qFq。
埃伦?约翰逊?瑟利夫2005年成为非洲第一位民主选举产生的女总统。挪威诺贝尔和平奖委员会赞扬她打破种族和宗教界限,帮助结束了利比利亚的内战。
台风艾玛
单词accomplished 联想记忆:

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

本麦克兰纳汗(Ben McLannahan)是美国银行业编辑
6) I find it hard to start a conversation 0 1 2 3 4

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

The demagogue’s campaign leads naturally to despotism — the tyranny of the majority that is a mask on the tyranny of one.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Finally, in the EMBA ranking, excluding joint programmes delivered with non-European schools, IMD of Switzerland, with an average salary of $261,397, is well ahead of Business School in second and IE Business School in third place.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
From the themed collection: 定制家具 O2O模式迎合消费习惯
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

或许纯粹是巧合,但Magento首位产品经理蒂姆o舒尔茨也刚刚加入Bigcommerce,出任产品管理高级副总裁。舒尔茨近年来担任谷歌Shopping Express、Wallet等服务的战略合伙和商业发展高管,未来将专注于Bigcommerce的一站式体验,将电子商务和实体零售更好地结合起来。“消费者想要无缝化体验,”他说。
WTF.1: Next Level of Working Moms
de加强动作+termine界限→加强界限→限定;决定
"We hold ourselves to a very high standard," Curry said. "We didn't put any pressure on them defensively in the third quarter. We were sloppy on a couple of possessions offensively and gave them life. Those are things we need to improve on. Everyone likes to learn those lessons in wins."

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

与此同时,苹果正在引入昂贵的新组件,包括OLED显示屏,使手机正面成为一个连续屏幕。深度感应摄像头将提供“增强现实”新功能,并允许手机通过人脸识别(而不是指纹)解锁。
失宠行业
We will use this painful adjustment on the part of government to ensure that things will be much more convenient and easier for our businesses to enhance their competiveness on the market.
It was all work, work, work for the BBC Culture team and parties, alas, were few and far between. But the rest of Cannes was painting the town red. In 2013 we tried to calculate the amount of champagne consumed at the festival by contacting Piper Heidsieck, “the official drink” of the festival, but they declined to comment – though judging by the merry faces and staggering gaits of some on the Croisette, it's safe to assume a colossal quantity. At the party for Matteo Garrone's Tale of Tales on the first weekend, the champers flowed freely and the revellers stayed on until the early hours. When the BBC's Rebecca Laurence spoke to one of its stars the following morning and asked how many hours sleep he'd had before their interview, he simply narrowed his bleary eyes and held up two fingers.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
From the themed collection: 陕西明确6项住房保障重点工作
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

5. 地缘政治事件。不久之前,石油供应稍有差池,油价就会飙升。比如说2014年初,利比亚内乱造成该国石油出口中断,油价应声上涨。在伊拉克, 极端组织ISIS领了部分地区,石油供应中断的顾虑也造成油价急剧攀升。然而,自此之后,地缘政治事件对油价的影响大为减弱。2014年最后几周,利比亚再现战事。但市场仅在油价短暂上扬后便把这一问题抛诸脑后。不过,历史一再证明,地缘政治危机是对油价影响最大的短期因素之一。(财富中文网)
control

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

10. China watchers inthe United States will continue to postulate China’s declining growth rate inthe face of evidence that it is stable at over 7%. China will grow fasterin 2014 than in 2013.
*Writing for a Variety Series: “Last Week Tonight With John Oliver”
会。梅亚德是执政党革命制度党(PRI)的候选人。他主要的竞争对手是强硬的左翼领导人安德烈斯曼努埃尔洛佩斯奥夫拉多尔(Andrés Manuel López Obrador)——可以感召人群的激情演说家。梅亚德需要克服很多问题:在去年1月一夜间把油价上调20%、引发通胀飙升后,他必须说服选民自己仍然是可以信任的。他还必须证明自己是个有主见的人,而不仅仅是这届不受欢迎的政府的傀儡——在遏制猖獗的腐败和犯罪行为方面,这届政府极为失败。但是凭借强大的PRI拉票机器,他可能势不可挡。在墨西哥只有一轮选举的体制下,30%的选票可能就足以让他当选总统了。
是的,一些模子会导致过敏反应和呼吸道症状。还有些模子在一些条件下会产生“霉菌毒素”,生成致病的有毒物质。
4.菲亚特 品牌喜爱度:-7%/排名:85

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

“Someone resigned via a video conference call.”
Enrollment: 503
The ranking is based on surveys of schools and alumni who graduated in2011. This edition gives a snapshot of alumni’s situation compared with when they started the programme.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

201109/155435.shtmlIn August, Jose Javier - from the city of Torrevieja - created an account with AdWords, a Google pay-per-click service.
Wang Ki-young, a director at South Korea’s culture ministry, said on Friday that Chinese authorities had ordered tourism agencies in Beijing to halt tours to South Korea from mid-March. Mr Wang said the move would be expanded to other provinces.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

白意味着属于一个外表、传统、宗教乃至食物都符合默认常规的群体。按照不言而喻的规则,白人意味着是一个长期被称作是“我们”,而不是“他们”中的一份子的人。
007系列电影主题曲第五名:保罗·麦卡特尼和Wings乐队--《生死关头》
奖项:尽管大众的高尔夫GTI先拔头筹,但偏向自家人的2015年北美汽车大奖的评审员们还是对福特的野马和F-150皮卡不吝溢美之辞。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Even if they played an imperfect game, the Golden State Warriors managed to maintain their perfect start.
n. 克制,控制,管制,操作装置
In the past two decades, several campus poisoning incidents have sparked mass debates and concerns about students' psychological development and support.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

以美元值计,11月中国的进口总值同比上升17.7%,比10月的17.2%高,高于11.3%的预期增速。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 宜家大手笔投资商业地产
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

The North has already warned that Park will "pay for his crimes in blood" if copies of the film make it across the border.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
From the themed collection: 农地入市焕发“沉睡”土地活力
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

"All I got was an extra hour on the bus to work, but I can't get a seat at the stadium," she said as she directed cars toward a mall's parking garage in Rio's wealthy southern zone.
"我认为机器会比人类更强大、更智能,但绝不会比人类更睿智。"马云如是说。“因为有一件事是肯定的:智慧、灵魂和心灵都是人类所拥有的东西,而机器永远不能享受失败、成功、友谊或爱情。”

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
From the themed collection: 唐山陶博会展览筹备进展顺利
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

美国的实际GDP在7-9月份内比去年同期增长了3.9%,这是官方上个月发布的数据。
Length of program: 22 months
demographic
Canadian schools continue to lose ground. Only three remain in the ranking compared with five last year and all fall about six places. Among these, Rotman School of Management at the University of Toronto is the highest ranked at 65, while Smith School of Business at Queen’s University is bottom of the table in 100th place.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
From the themed collection: 取消木地板消费税呼声日益高涨
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

伦敦商学院在所有这4项排名上表现强劲,包括全日制MBA课程排名第一,合办EMBA(与美国哥伦比亚商学院(Columbia Business School)合办)和定制高管教育课程均排名第三。
The letter mysteriously arrived at the California University of Pennsylvania, in the north-eastern state of Pennsylvania, 10 days ago. Written to Mr Moore, the two-page letter was postmarked 20 February 1958 and signed "love forever Vonnie".

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

在第一部掌上移动设备发明之前,自拍杆已经问世。自拍杆其实是由一个日本男人上田宏在20世纪80年代发明的。上田宏是美能达相机公司的摄影师,他发明这个自拍杆,是因为他和妻子在欧洲旅行时无法自拍合照。(当时,他叫一个男孩帮他们拍照,那个男孩却拿着相机跑了。)
现在似乎可以放心地预言,2017年余下时间会出现更多噪音、甚少进展,而这将继续对贸易和英国经济造成破坏。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: LED照明企业向三四线城市谋发展
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Newt Scamander is a magiczoologist who studies magical creatures.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

reg统治,ulate-管制
smiles and puma snarls
Ladies and gentlemen, may I welcome you to the Bad Manners Awards 2016?
Wishing you peace, joy and happiness through the coming year.在新年来临之际,祝福你平安、快乐、幸福!

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

同时,根据这一最新调查显示,2015年我国男女比例的差距也有所缩小。从性别构成看,男女人口性别比例已由2010年的105.2降至去年的105.02。
Or, this year, to be women with a story to tell about abuse, sexual or otherwise — a couple of whom shared #MeToo moments in our pages. Carlotta Gall told the story of Henda Ayari, a French citizen of North African heritage and anti-Salafist activist who accused a prominent Oxford professor of raping her.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

办事处副局长卢华东说:“自治区已投资40亿元人民币(约合6亿美元),用于推动贫困地区特色的产业,去年重新安置了77000名贫困人口。”
该调查讨论了对未来的预测:"生活成本总是变化的,来年将发生的变化已经有了迹象。"
完成所有的事,甚至更多

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

n. 基金;资金,现金(fund的复数) v. 提供资金
在美国,纽约州、加利福尼亚州和得克萨斯州获得最多投资。中国企业在头号投资目的地纽约投资54亿美元,其中大部分投入三笔大规模金融服务和房地产交易。
China’s forex reserves — the world’s largest — have long been seen as the ultimate guarantor of financial stability, since they can be used to hedge against capital flight or to bail out domestic financial institutions struggling with a rise in bad debts.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Chen Yu, vice-president of the China Association for Employment Promotion, said a startup may be meaningful, but one should not expect too much from it.
Warm greetings and best wishes for the New Year!致以热烈的祝贺和良好的祝福,新年快乐。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

“This growth is further backed by Video Editing making an appearance at number 3 on the list with a 19% increase,” the report states, “as video content becomes one of the initial draws and call to actions for most customer-focused websites. Heavy video marketing through social media also increases this demand.”
人们可能会认为,由于课程的灵活性,与全日制项目相比,在线MBA项目将更吸引女性。然而,2016年英国《金融时报》在线MBA排行榜的数据显示,女性占总学员数量的30%。在全日制项目中,女学员占到了35%。
罗杰斯夫人还表示,正如条款中所述,她并没有同意她的儿子玩这个游戏。此外,由于这个游戏是免费的,所以该工作室不能够断言因为作弊软件而造成了利润损失。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 旧楼加装电梯价格立涨?
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

With the compliments of the season.
Actively expanding China's opening up to the world

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

这位官员表示,相比其他职位来说,那些对教育背景或工作经历没有特殊要求的职位更受欢迎,近些年报名人数达到数千人的基本上都是这种职位。
波多黎各人自前任总督的过去4年受到了几十项新税收的影响,还增加了水电费。加西亚·帕迪利亚设法为政府创造更多的收入,他说资金正在用尽。尽管有某些和那些措施,岛上政府已经违约上百万美元的债券付款,数个机构宣布进入紧急状态。
衡量散货大宗商品贸易的波罗的海干散货运价指数(BDI)已经触及历史低位。2014年超过美国成为世界最大贸易国的中国本月报告,1月出口和进口都出现两位数下降。正在经历一个多世纪以来最严重衰退的巴西从中国的进口暴跌。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

n. 经营方法,行为态度

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

If you have been out of work for a long time, it may be time to consider taking a job you wouldn't have looked at before.
Angela Merkel's salary as German chancellor is set at 218,400 euros a year ($242,000). The chancellor got a 2% pay rise at the beginning of March, and will get another 2% next February.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Unlicensed drivers who engage in the services will face a fine ranging from 10 thousand yuan ($1,500) to 30 thousand yuan ($4,500).
自信和出色的“电梯演说”可以提高推销的水平。任何一家公司最早的市场营销经验都来自它的创始人。因此,花时间学习如何分享你的愿景,但不要给人留下“你只是想卖东西”的印象。不要害怕寻求销售机会,但你应该牢牢记住:永远以客户为中心。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

In addition to the overall ranking, US News also offers region-, country- and subject-specific rankings, to allow for more tailored searching.
protocol

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

与去年相比,亚马逊(Amazon)、星巴克(Starbucks)和Facebook今年的品牌价值飙升。亚马逊的品牌价值增长59%,至990亿美元,排名第七,Elspeth Cheung表示,这在一定程度上源于其创造需求、而不仅仅是满足需求的能力。她表示,亚马逊的一小时送货服务对其他零售商加快送货速度构成压力,同时这家在线零售商进入物流领域对联合包裹(UPS)、联邦快递(FedEx)以及DHL等快递公司构成威胁。
Mr Cook’s lack of showmanship has not always been seen as an asset.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 瓷砖洁具市场热门关键词汇总
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

The paperpot transplanter allows a single person to transplant 264 plants covering over 85ft in just minutes. What used to take hours, now takes minutes. Allowing you to spend less time transplanting crops, and more time doing other things like farm improvements, marketing, sales, or just taking some time off.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Ahead of the release, economists at ANZ said they expected inflation to pick up in January owing to rising food prices, and the low commodity prices would weigh on the CPI.
vaccine
? Aid workers are worried about a food crisis in Haiti, where Hurricane Sandy killed 52 people last week. The UN is also concerned that flooding could lead to a sharp rise in cholera cases. At least 69 people were killed by Sandy in the Caribbean.
单词regulate 联想记忆:

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Here are some of the trends that emerge from this year’s BrandZ rankings:

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

Emma Morano
Last year he told an interviewer that 'among others' he would be giving his riches to Choupette.
201011/117323.shtmlThe French actress will star alongside Ryan Gosling, Michael Fassbender and Natalie Portman.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Emily Ratajkowski managed to steal the show, opting for a seriously saucy twist on the classic ballgown. Opting for a semi-sheer lacey black number, the We Are Your Friends actress ensured her world-famous figure was on display.
英国门萨首席执行官约翰·斯蒂门尼奇说他为妮诗感到高兴。他说:“我希望她能充分利用好成为门萨会员的机会,结交志趣相投的新朋友,不断挑战自己。加入门萨,就为你打开了一扇大门。门萨是一个会员超过10万人的世界网络,很多会员会成为终生好友。”

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

A total of 13.14 million new urban jobs were added.
在攻读EMBA课程之初,男女学员的简单情况基本类似。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

《老友记》是成长在90年代的小伙伴们心中标志性的存在,因为它的主题:友谊、大城市生存的不易,发现自我、寻求独立,与年轻人息息相关,如今亦是如此。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 明年个税缴多少应该怎么算
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Fifteen Chinese nationals have been charged with developing a fraud scheme in which they paid imposters to take entrance exams, including the SAT, and gained acceptance to elite American colleges and universities, the US Department of Justice said on Thursday. Conspirators were paid up to $6,000 each time they used counterfeit Chinese passports to trick test administrators into thinking they were the person who would benefit from the test score, a federal grand jury charged.重点单词
4. Slacking at school
单词statement 联想记忆:

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 泉州建材市场火烧连营
Paper

Length-scale dependence of protein hydration-shell density

2016年全球创新指数排名靠前的经济体中,日本、美国、英国、德国在创新质量方面表现突出。
Golden State righted itself over the next few months. Kevin Durant suffered an injury which let Stephen Curry be Stephen Curry again, and when Kevin Durant returned, the team had found a balance between their two MVPs. The result was a terrifying burst through the playoffs, as the Warriors swept the Western Conference playoffs. Portland offered no resistance. Utah put up a noble effort but still couldn't get a game. The Spurs led by 20 ... and then Kawhi Leonard went down with an injurywhen Zaza Pachulia stuck his foot out, and that was that.
7.Manage up, down, and sideways
而分子马达将会为医药和能源领域带来巨大的潜力。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

5. 艾玛?斯通
为了让世界都关注濒危物种和中国成都大熊猫基地,演出者们全力表演,节目精彩令人难以忘怀。他们不仅给伦敦市民带去了乐趣,还与基地大使、自然主义者奈杰尔-马文一同去学校向孩子们宣扬熊猫保护的理念。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

在领英平台上高频出现是找工作的关键。你知道这点,你们经理也知道这点。你的经理兴许还知道你知道这点。所以她会从开始关注周一你的个人简介只是有个大概框架,到周五你增加了工作经历,新人脉,状态更新,推荐信慢慢被顶起,别一夜之间从0涨到500那样太明显了Foss提醒道。
波德斯塔接受《波斯顿环球时报》采访时表示:"我们有一个备选充足的名单,然后再逐渐缩小选择范围。但毫无疑问地是,这份名单上将有女性。"
Collins grew up in rural, apartheid-era South Africa in the 1970s. Her childhood inspired her to focus on empowering women living below the poverty line through grassroots efforts. The Wonderbag, which was inspired by watching her grandmother cook with cushions, uses heat retention technology to cook food for 8-12 hours without the need for additional fuel. Collins witnessed the benefits African women received from using Wonderbags, reducing the amount of time they spent collecting firewood. For every bag sold, another is donated to a household in Africa, and in the past four years, the Wonderbags have found themselves in 600,000 African homes. Collins has launched the Wonderbag in the U.S. on Amazon, and hopes to sell the products via other retailers by 2014.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

Callabro,喜欢唱歌剧的男孩组合在经过不懈努力之后成功成为了本年度的英国达人秀冠军,最具天赋的歌唱组合。
11月22日,马拉比在伦敦的一场晚宴上领取了该奖。英国电信集团TalkTalk行政总裁迪多.哈丁(Dido Harding)应邀在晚宴上发表了演讲。

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